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Crucially, unlike full-length hGH, AOD-9604 does not significantly elevate IGF-1 levels or negatively impact glucose tolerance, contributing to its favorable safety profile in clinical studies
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The lack of immunogenicity has practical implications: the peptide can be used for extended periods without loss of efficacy due to antibody neutralization, there is minimal risk of allergic or hypersensitivity reactions, and repeated treatment cycles are supported as prior exposure does not sensitize the immune system
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